{"id":51990,"date":"2021-11-03T14:12:56","date_gmt":"2021-11-03T13:12:56","guid":{"rendered":"https:\/\/smarthealth.live\/?p=51990"},"modified":"2021-11-03T14:58:09","modified_gmt":"2021-11-03T13:58:09","slug":"better-therapeutics-societe-specialisee-dans-les-medicaments-dtx-fait-son-entree-en-bourse","status":"publish","type":"post","link":"https:\/\/smarthealth.live\/fr\/2021\/11\/03\/better-therapeutics-societe-specialisee-dans-les-medicaments-dtx-fait-son-entree-en-bourse\/","title":{"rendered":"Better Therapeutics, soci\u00e9t\u00e9 sp\u00e9cialis\u00e9e dans les m\u00e9dicaments DTx, fait son entr\u00e9e en bourse"},"content":{"rendered":"

Better Therapeutics, bas\u00e9e \u00e0 San Francisco, est cot\u00e9e au Nasdaq depuis la semaine derni\u00e8re. La soci\u00e9t\u00e9 DTx<\/a> est sp\u00e9cialis\u00e9e dans les traitements num\u00e9riques des maladies cardiom\u00e9taboliques, en favorisant des changements de comportement chez les patients.<\/strong><\/p>\n

Better Therapeutics a \u00e9t\u00e9 fond\u00e9e en 2015. En \u00e0 peine 6 ans, elle a d\u00e9j\u00e0 lev\u00e9 plus de 70 millions de dollars d'investissements. Derni\u00e8rement elle a \u00e9t\u00e9 introduite en bourse par le biais d'une SPAC (Special Purpose Acquisition Company<\/em>). Il s\u2019agit de soci\u00e9t\u00e9s sans activit\u00e9 commerciale qui l\u00e8vent des fonds par le biais d'une cotation en bourse. Ces derni\u00e8res fusionnent avec une entreprise existante ou l'acqui\u00e8rent. Ici, Mountain Crest Acquisition Corp II a fusionn\u00e9 avec Better Therapeutics. Contrairement \u00e0 une introduction en Bourse traditionnelle qui prend plusieurs mois, le processus SPAC ne dure g\u00e9n\u00e9ralement que quelques semaines. Better Therapeutics peut \u00eatre n\u00e9goci\u00e9 sur le NASDAQ sous le titre BTTX.<\/p>\n

Solutions DTx Meilleure th\u00e9rapeutique<\/h3>\n

L'entreprise se concentre actuellement sur le lancement du BT-001. Cette solution DTx est destin\u00e9e aux patients atteints de diab\u00e8te de type 2. Ainsi, sous la supervision d'un m\u00e9decin, BT-001 tente de faire baisser le taux d'HbA1c par un changement de comportement. L'HbA1c est une mesure de la moyenne de la glyc\u00e9mie. La solution DTx combine divers facteurs cliniques, comportementaux et psychologiques dans des le\u00e7ons et des modules de th\u00e9rapie. L\u2019objectif est de faire acqu\u00e9rir de nouvelles comp\u00e9tences comportementales aux malades.<\/p>\n

Better Therapeutics s'efforce de faire passer le BT-001 par des essais cliniques pour ensuite envisager une autorisation de la FDA. Actuellement, la soci\u00e9t\u00e9 \u00e9tudie le traitement chez les personnes dont le diab\u00e8te n'est pas contr\u00f4l\u00e9. En effet, en coop\u00e9ration avec le prestataire de soins primaires Catalyst Health Network, les premiers patients viennent de recevoir l'outil DTx afin de d\u00e9terminer les r\u00e9sultats sur le long terme.<\/p>\n

D\u2019autres solutions DTX se profilent \u00e0 l'horizon. \u00c0 savoir des outils permettant de r\u00e9duire le cholest\u00e9rol en cas d'hyperlipid\u00e9mie, de r\u00e9duire les triglyc\u00e9rides en cas d'hypertriglyc\u00e9rid\u00e9mie et de r\u00e9duire la pression art\u00e9rielle systolique (sup\u00e9rieure) et diastolique (inf\u00e9rieure) chez les patients souffrant d'hypertension.<\/p>\n

Pr\u00e9valence \u00e9lev\u00e9e des maladies cardiom\u00e9taboliques<\/h3>\n

Le cofondateur et P.D.G. de Better Therapeutics, Kevin Appelbaum, est convaincu du fort potentiel des th\u00e9rapeutiques num\u00e9riques. Pour lui, elles repr\u00e9senteront la premi\u00e8re ordonnance que les m\u00e9decins r\u00e9digeront pour traiter les causes des maladies \u00e9vitables. Better Therapeutics indique que la moiti\u00e9 des adultes sont touch\u00e9s par trois affections cardiom\u00e9taboliques li\u00e9es, entre autres, au mode de vie. Il s\u2019agit du diab\u00e8te, de l'hypertension art\u00e9rielle<\/a> et du mauvais cholest\u00e9rol. Cela repr\u00e9senterait 80 % des co\u00fbts des soins de sant\u00e9 aux \u00c9tats-Unis.<\/p>\n

Selon la soci\u00e9t\u00e9 bas\u00e9e \u00e0 San Francisco, des interventions sur le r\u00e9gime alimentaire et le mode de vie permettraient de r\u00e9duire ces probl\u00e8mes. Il s'agit notamment d'arr\u00eater de fumer, de r\u00e9duire la consommation d'alcool, de faire plus d'exercice, de manger plus sainement et de mieux contr\u00f4ler son poids. L'entreprise souligne que ces solutions DTx permettront, en fin de compte, de lib\u00e9rer plus d'argent pour traiter les patients atteints d'une maladie in\u00e9vitable.<\/p>\n

DTx et changement de comportement<\/h3>\n

Selon le cofondateur David Perry, le changement de comportement bas\u00e9 sur les logiciels a fait ses preuves. Il fait r\u00e9f\u00e9rence \u00e0 l'utilisation de jeux et d'applications tels que Facebook, Uber et Fitbit. Il cite l'exemple d'un patient qui va rarement chez le m\u00e9decin. Finalement, il ne va interagir qu\u2019une seule fois avec un professionnel de sant\u00e9, et seulement durant quelques minutes. M\u00eame si les conseils seront les m\u00eames, la personne sera peu sensibilis\u00e9e au quotidien. En revanche, via l\u2019application, elle sera beaucoup plus \u00e0 l\u2019\u00e9coute puisqu\u2019en moyenne l\u2019application DTx est consult\u00e9e 11,5 fois par jour. Pour appuyer ses propos, il fait r\u00e9f\u00e9rence \u00e0 des \u00e9tudes cliniques ant\u00e9rieures sur les solutions DTx pour les patients souffrant d'hypertension art\u00e9rielle et de diab\u00e8te. Ainsi, il affirme qu'apr\u00e8s 12 \u00e0 16 semaines, l'utilisation du DTx avait presque le m\u00eame effet positif par rapport aux patients utilisant uniquement des m\u00e9dicaments.<\/p>\n

David Perry mentionne quatre avantages importants du DTx par rapport \u00e0 l\u2019usage des m\u00e9dicaments.<\/p>\n

    \n
  1. Ils ne provoquent pas d'effets secondaires,<\/li>\n
  2. les co\u00fbts sont plus faibles,<\/li>\n
  3. les applications s'am\u00e9liorent (apprentissage automatique),<\/li>\n
  4. et les DTx deviennent donc moins on\u00e9reux.<\/li>\n<\/ol>\n

    Ainsi, selon lui, une meilleure technique logicielle permet de r\u00e9duire les co\u00fbts par patient. Et cela contraste avec les m\u00e9dicaments dont le prix augmente chaque ann\u00e9e.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Les solutions num\u00e9riques visent \u00e0 modifier le comportement des patients atteints de maladies cardiom\u00e9taboliques.<\/p>\n","protected":false},"author":42,"featured_media":51954,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4648,4650],"tags":[5385,5386,5387,4931,5390,5388,5389,5391],"class_list":["post-51990","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-digital-therapeutics-fr","category-financement","tag-better-therapeutics","tag-bourse","tag-bt-001","tag-diabete","tag-dtx-fr","tag-essais-cliniques","tag-maladies-liees-au-mode-de-vie","tag-therapeutiques-numeriques"],"acf":[],"yoast_head":"\nBetter Therapeutics, soci\u00e9t\u00e9 sp\u00e9cialis\u00e9e dans les m\u00e9dicaments DTx, fait son entr\u00e9e en bourse - Smarthealth<\/title>\n<meta name=\"description\" content=\"Les solutions num\u00e9riques visent \u00e0 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